5x01 "Unusual Suspects"

• Robson Square Conference Centre, 600 Robson St.: Baltimore Convention Center
• Dominion Building, 207 West Hastings St., Gastown: Baltimore Guardian newspaper group [photo]

5x02 "Redux"

• Yellow Pages/Dominion Directory, 4260 Still Creek Dr., Burnaby: Defense Advanced Research Projects Agency, exterior and lobby [in "Gethsemane," this building is labeled as Department of Defense, Research Division, Sethsburg, Virginia]
• Justice Institute, 715 McBride Blvd., New Westminster: Defense Advanced Research Projects Agency, interior
• Fraserview Bldg, Woodlands Hospital: Defense Advanced Research Projects Agency, hallway
• Open Learning Agency, 4355 Mathissi Pl., Burnaby: Pentagon warehouse

5x03 "Redux II"

• Hastings Park Racecourse, Exhibition Park: Racetrack
• Atrium Inn, 2889 E. Hastings St.: Staircase to assassin's lookout
• 2 Jays Cafe, 81 West Pender Street: Diner, site of the Mulder family reunion
• 400 block of W. Cordova St., Gastown: Downtown Georgetown, site of Mulder's meeting with the Cigarette-Smoking Man

5x04 "Detour"

• Seymour Demonstration Forest, North Vancouver: Route 43, Leon County, Florida and surrounding forest [see map from X Marks the Spot]
• Lions Gate Travelodge, 2060 Marine Drive, North Vancouver: Motel (Scully, room 224; Mulder, room 222) [photo]

5x05 "Christmas Carol"

• Ortona Cres., Dept. of National Defence (DND) Jericho Base: Bill Scully Residence, U.S. Naval Station, San Diego, California
• 3106 Alberta St.: Sim residence, San Diego

5x06 "Post-Modern Prometheus"

• Muskrat Meadow, Deas Island Regional Park, Delta: Site of peanut butter sandwich trap [photo] (Also featured on the cover of X Marks the Spot)
• Maplewood Flats Wildlife Sanctuary, 2600 block Dollarton Hwy, North Vancouver: Hillside on property of Farmer Pollidori
• Burrvilla, Deas Island Regional Park, Delta: Dr. Pollidori's House [photo]
• Read House, 2981 41B St., Delta: Farmer Pollidori's house and barn
• Post Office, Ladner: Post office

5x07 "Emily"

• Ortona Cres., Dept. of National Defence (DND) Jericho Base: Bill Scully Residence, U.S. Naval Station, San Diego, California
• Glen Hospital, 1036 Salsbury Dr.: Retirement home

5x08 "Kitsunegari"

• Old Boiler Room, George Pearson Hospital, West 57th Ave.: Lorton Penitentiary cafeteria, Washington, D.C.
• Great Outdoors, 201 Lonsdale Ave, North Vancouver: Sporting goods store, Occoquan, Virginia [photo]

5x09 "Schizogeny"

• Hazelgrove Farms, Ft. Langley: Hazelnut orchard, Coats Grove, Michigan

5x10 "Chinga"

• Shop Easy, 2535 Shaughnessy St., Port Coquitlam: Supr Savr supermarket, Ammas Beach, Maine
• Marine Dr., White Rock: Main street, Ammas Beach
• Save On Gas, Brooksbank Av., North Vancouver: Gas station, Ammas Beach [photo]
• Crescent Beach, White Rock: Wee Lassies and Laddies Daycare

5x11 "Kill Switch"

• Vancouver waterfront: Shipping container lot
• Back lot at BFI Recycling, Burnaby: Shipping container explosion
• Read House, 2981 41B St., Delta: Derelict chicken farm with T3 connection, Fairfax County, Virginia
• Near Boundary Bay Airport: Trailer, Fairfax County
• Westham Island Bridge, Canoe Pass, Delta: Swingspan bridge [photo]

5x12 "Bad Blood"

• Tolko Industries site, 200 Bridge Street, North Vancouver: Rolling Acres RV Camp, Cheney, Texas

5x13 "Patient X"

• Gravel Pit, Seymour Demonstration Forest: Forest and clearing, Kazakstan, Former Soviet Union [see map from X Marks the Spot]
• Port Mann Substation, 14115 King Road, Surrey: Boiler room, Uroff-Koltoff Star of Russia
• Seymour Demonstration Forest: Skyland Mountain National Park, Virginia
• Outside of psych hospital in Burnaby: Phone booth, Scudder Road, off I-90
• Ruskin Dam, Dewdney Trunk Rd., between Ruskin and Mission: Ruskin Dam, Pennsylvania [see photos here and at X-Town]

5x14 "The Red and the Black"

• Grouse Mountain: CSM's cabin, R. R. # 1, North Hatley, Quebec, Canada
• Ruskin Dam, Dewdney Trunk Rd., between Ruskin and Mission: Ruskin Dam, Pennsylvania [see photos here and at X-Town]
• BC Children's and Women’s Health Centre: Memorial Hospital, Washington, D.C.
• Stokes Pit, South Surrey: UFO crash site, Wiekamp Air Force Base
• BC Parks Works Yard, Base of Seymour Mountain, North Vancouver: Main gate, Wiekamp Air Force Base

5x15 "Travelers"

• 18237-16 Ave., Surrey: Old Man Skur’s rental house, Caledonia, Wisconsin
• The Meatmarket Restaurant, 1 West Cordova Street, Gastown: The Hoot Owl Bar, Washington, D.C. [see photo at X-Town]
• Country road near U.S. border, Surrey: Rural road, site of Skur's liberation by Bill Mulder

5x16 "Mind's Eye"

• Blarney Stone Pub, 216 Carrall Street, Gastown: The Blarney Stone Inn, Wilmington, Delaware [photo 1, photo 2]
• Hastings Park Racecourse, Exhibition Park: French St. Bus Terminal, Wilmington, Delaware

5x17 "All Souls"

• 500 block of East 12th St., North Vancouver: Kernof residence
• St. Augustine's Parish, 2028 West 7th Ave: St. John's Church, Alexandria, Virginia [photo 1, photo 2]
• Old Boiler Room, George Pearson Hospital, West 57th Ave.: Church of St. Peter the Sinner
• Station Street: Rundown neighborhood, Washington, D.C.

5x18 "Pine Bluff Variant"

• Rose Garden, Stanley Park: Folger Park, Washington, D.C. [photo]
• 2400 Court Motel, 2400 Kingsway: Aaron Burr Motor Court, Angola, Delaware (Room 130?) [photo]
• Dunbar Theatre, 4555 Dunbar Street: Dunbar Theater, Gables Corner, Ohio [see photo at X-Town]
• 1010 Salsbury St.: Mulder's apartment building, 2630 Hegal Place, Alexandria, Virginia, exterior
• Bank of Canada, 900 W. Hastings: First Sovereign Bank of Pennsylvania, Harrisburg, Pennsylvania [photo]

5x19 "Folie a Deux"

• 12340 Horseshoe Way, Richmond: VinylRight Corporation, Oak Brook Illinois, exterior
• 1950 Cedar Village Crescent, North Vancouver: Gary Lambert Residence, Oak Brook, Illinois (Apt. 87?) [photo 1, photo 2]
• 500 block East 11th St., North Vancouver: Starns residence

5x20 "The End"

• General Motors Place, 800 Griffiths Way: Chess tournament, Vancouver, British Columbia [see photo at X-Town]
• Riverview Hospital: Federal Detention Facility, Ft. Marlene, Maryland; Ignet Murray Psychiatric Hospital
• Avalon Hotel, 1025 Marine Drive, North Vancouver: Avalon Hotel, site of CSM's encounter with WMM and Kryceck [photo]
• London Guard Motel, 2277 Kingsway: Motel, Centerville, Virginia [photo 1, photo 2]
• Skytrain overpass next to GM Place: Empty lot, site where CSM hands over Gibson